NIDA

NIDA Research: Reduced Activity in One Brain Region Links Childhood Adversity to Aggression/Delinquency and Substance Use in Adolescents

Publication Date: Oct 12, 2021
NIDA Research

NIDA Research:

Reduced Activity in One Brain Region Links Childhood Adversity to Aggression/Delinquency and Substance Use in Adolescents

 

This study found that:

 

  • People who experienced more childhood adversity had higher rates of substance use in late adolescence.

 

  • Children who experienced adversity were more likely to show externalizing behavior (e.g., aggression, delinquency) in early adolescence, which in turn predicted substance use in late adolescence.

 

  • Reduced activation of the brain’s anterior cingulate cortex mediates the relationship between childhood adversity and increased externalizing behavior.

 

brain

Illustration of brain regions studied in mental illness: ACC, amygdala, hippocampus, prefrontal cortex. (Photo credit: NIH)

 

To read the full article, go here: https://www.drugabuse.gov/news-events/nida-notes/2021/08/reduced-activity-in-one-brain-region-links-childhood-adversity-to-aggression-delinquency-and-substance-use-in-adolescence?utm_source=daRSS&utm_medium=email&utm_campaign=da-researcherdigest