While evidence-based approaches to prevention are being strongly supported by policy makers of late, it isn’t always clear what this means and how it might relate to your own work in the field. This webinar is an overview of prevention science and how it has brought about the development not only of effective prevention programs but also to the planning and implementation of these. Evidence-based programs have been shown through rigorous research to be successful at reducing risky and unhealthy behaviors across the life span. This webinar describes how the science contributes to our understanding of the etiology and prevention of substance use and related behaviors, examples of some of the most effective interventions and policies.