The goal of this 1 hour presentation is to effectively introduce the MY-SBIRT Project and outline the main components & best practices for implementing universal substance use screening for adolescents using the CRAFFT 2.1 + N and Rapid Assessment for Adolescent Preventive Services tools. While this presentation is specific to the screening protocol developed for School-Based Health Centers through the MY-SBIRT Project, the key elements for administering screening, engaging adolescents in motivational interviewing & brief negotiated interview techniques, and best practices for connecting individuals identified as higher risk to appropriate support & treatment can be applied to any clinical environment that serves adolescents.