The Central East PTTC serves the U.S. Department of Health and Human Services Region 3, which includes Delaware, Maryland, Pennsylvania, Virginia, West Virginia, and the District of Columbia. The PTTC will provide technical assistance (TA) and training (T) geared toward developing and strengthening the capacity of substance use prevention field to provide services that are based on prevention science and use evidence-based and promising practices. The populations of focus are prevention professionals and organizations, community coalitions, social service groups, other community based and faith based organizations, minority-specific organizations, healthcare workers, organizations, pre-professionals, peers, consumers and family members, and other stakeholders.