The South Southwest Prevention Technology Transfer Center (South Southwest PTTC), based out of the University of Oklahoma, Outreach, serves substance misuse prevention professionals, organizations, and state, tribal, and community stakeholders in five southwestern states by providing high-impact training and technical assistance. Our work helps build the professional and community capabilities required to deliver effective and evidence-based prevention programs, practices, and strategies. The South Southwest PTTC is part of U.S. Health and Human Services Region 6, serving Arkansas, Louisiana, Oklahoma, New Mexico, and Texas.