This course will cover the basics of adolescent brain development, how substance misuse can impact brain development and behavior, and how differences in age of initiation, and using other substances may influence brain development. Highlighting findings from the multisite longitudinal Adolescent Brain Cognitive Development (ABCD) Study and the University of California San Diego Department of Psychiatry’s Tobacco-Cannabis study, this course provides the latest information on research in this area. By the end of the course, participants will be able to: 1. Describe the basics of adolescent brain development. 2. Identify how adolescent substance use impacts brain development and behavior. 3. Explain how pre-existing neural differences, age of initiation, and co-occurring substance use may influence neurodevelopment in adolescent substance users. 4. Demonstrate an understanding of the ABCD Study. 5. Summarize kef findings related to the study of cannabis and nicotine in the brain. Certificate of Completion Available