Prevention leaders are dedicated to improving the health of their communities through effective programs and policies to reduce substance misuse and its related consequences. Perhaps the most critical decisions prevention staff weigh are what set of programs and policies to implement, typically with limited resources. In the past, many prevention practitioners relied on a single registry to find potential evidence-based programs and policies that is no longer available. The good news is many other options exist! This document summarizes many available federal registries and online databases where prevention practitioners can begin their search for the “best fit” evidence-based prevention program, policy, or practice.